Spironolactone
7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone; |7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone; SC-9420; Adactone
Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.
Synonyms
7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone; 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone; SC-9420; Adactone
Molecular Formula
C₂₄H₃₂O₄S
Appearance
White to Pale Beige Solid
Solubility
Chloroform (Slightly), Methanol (Slightly, Heated)
Storage
Refrigerator, 4°C
