Technical Data

289444
CAS Number
68880-55-7
Grade
Highly Purified
Molecular Formula
C49H82N2O18
Molecular Weight
989.19
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Spiramycin Adipate
Spiramycin adipate; Spiramycin, Hexanedioate (salt); Suanovil; 2-((4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-(((5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl)acetaldehyde adipate; Hexanedioic Acid, Compd. With Spiramycin; Mamivert; ; Spiramycin, Hexanedioate (salt); Suanovil

Spiramycin Adipate is an antibiotic that is used in biological studies in the role of multidrug resistance of Strenotrophomonas maltophilia. Spiramycin adipate is a drug that belongs to the group of antibiotics. It is a macrolide antibiotic which inhibits bacterial growth by binding to the 50S ribosomal subunit. Spiramycin adipate has been shown to have an inhibitory effect on experimental septicemia in animals and is effective against Streptococcus species. Spiramycin adipate also has a synergistic effect with erythromycin, which may be due to its hydroxyl group, which binds to the 16S ribosomal RNA in bacteria and prevents protein synthesis.

Synonyms
Spiramycin adipate; Spiramycin, Hexanedioate (salt); Suanovil; 2-((4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-(((5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl)acetaldehyde adipate; Hexanedioic Acid, Compd. With Spiramycin; Mamivert; ; Spiramycin, Hexanedioate (salt); Suanovil
CAS No
68880-55-7
Molecular Formula
C49H82N2O18
Molecular Weight
989.19
Appearance
White to off-white powder
Purity
≥95%
1H-NMR
Conforms to reference
Melting Point
>124ºC (dec.)
Solubility
DMSO (Slightly), Methanol (Slightly)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Huang, Y., et al.: J. Antimicrob. Chemother., 68, 1987 (2013); Poole, K., et al.: Mol. Microbiol., 21, 713 (1996)
USBio References
No references available
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