D-AP5 CAS 79055-68-8

Subscribe to our newsletter!

Welcome | LOG OUT

366877 D-AP5 (2-APV, 5 Phosphononorvaline, (2R)-2-amino-5-phosphonopentanoic acid) CAS: 79055-68-8

Specifications

References

CAS Number

79055-68-8

Grade

Highly Purified

MDL Number

MFCD00078839

Molecular Formula

C5H12NO5P

Molecular Weight

197.1

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. D-AP5 is reported to be the most active form of AP5 and is used in the research of synaptic plasticity.

Synonyms

2-APV, 5 Phosphononorvaline, (2R)-2-amino-5-phosphonopentanoic acid

CAS Number

79055-68-8

Molecular Formula

C5H12 NO5

Molecular Weight

197.1

Purity

≥95%

Applications

Appearance

Crystalline solid

Storage

Soluble in organic solvents such as DMSO. DMSO up to 5mg/ml. Product should be kept at -20°C.

References

1. Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus, 9(2), 118-136. 2. Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience, 9(9), 3040-3057. 3. |Davies, J., & Watkins, J. C. (1982). Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain research, 235(2), 378-386.