Technical Data

366888
CAS Number
147591-46-6
Grade
Highly Purified
MDL Number
MFCD00593367
Molecular Formula
C16H14N2O4
Molecular Weight
298.3
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
ID-8
ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838
Synonyms
ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838
Chemical Name
1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol
Molecular Formula
C16 H14 N2O4
Molecular Weight
298.3
CAS Number
147591-46-6
Purity
≥98%
Applications
FA
Appearance: Crystalline solid
Description
ID-8 inhibits tyrosine phosphorylation-regulated kinases and is used to maintain the pluripotency and sustain self-renewal of mouse embryonic stem cells. It is also reported to stimulate proliferation and enhance Wnt-mediated human embryonic cell survival
Storage
Soluble in organic solvents such as DMF and DMSO.
Purity
Highly Purified (~98%)
Concentration
Not determined
Form
Supplied as a crystalline solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Kochegarov, A. (2009). Small molecules for stem cells. 2. Hasegawa, K., Yasuda, S. Y., Teo, J. L., Nguyen, C., McMillan, M., Hsieh, C. L., & Kahn, M. (2012). Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.Stem cells translational medicine, 1(1), 18-28. 3. Miyabayashi, T., Yamamoto, M., Sato, A., Sakano, S., & Takahashi, Y. (2008). Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Bioscience, biotechnology, and biochemistry, 72(5), 1242-1248.
USBio References
No references available
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