ID-8 CAS 147591-46-6

CAS Number

147591-46-6

Grade

Highly Purified

MDL Number

MFCD00593367

Molecular Formula

C16H14N2O4

Molecular Weight

298.3

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838

Synonyms

ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838

Chemical Name

1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol

Molecular Formula

C16 H14 N2O4

Molecular Weight

298.3

CAS Number

147591-46-6

Purity

≥98%

Applications

Appearance: Crystalline solid

Description

ID-8 inhibits tyrosine phosphorylation-regulated kinases and is used to maintain the pluripotency and sustain self-renewal of mouse embryonic stem cells. It is also reported to stimulate proliferation and enhance Wnt-mediated human embryonic cell survival

Storage

Soluble in organic solvents such as DMF and DMSO.

Purity

Highly Purified (~98%)

Concentration

Not determined

Form

Supplied as a crystalline solid.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Kochegarov, A. (2009). Small molecules for stem cells. 2. Hasegawa, K., Yasuda, S. Y., Teo, J. L., Nguyen, C., McMillan, M., Hsieh, C. L., & Kahn, M. (2012). Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.Stem cells translational medicine, 1(1), 18-28. 3. Miyabayashi, T., Yamamoto, M., Sato, A., Sakano, S., & Takahashi, Y. (2008). Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Bioscience, biotechnology, and biochemistry, 72(5), 1242-1248.

USBio References

No references available

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366888 ID-8 CAS: 147591-46-6

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MDL Number

Molecular Formula

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EU Commodity Code

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ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838

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USBio References

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