Technical Data

440675
Grade
Highly Purified
Molecular Formula
C14H21N6O10P3 • xC6H15N
Molecular Weight
526.27
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Abacavir Triphosphate TEA Salt

Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Molecular Formula
C14H21N6O10P3 • xC6H15N
Solubility
Methanol (Slightly), Water (Slightly)
Molecular Weight
526.27
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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