Technical Data

444174
CAS Number
497223-25-3
Grade
Highly Purified
Molecular Formula
C41H52N4O4S
Molecular Weight
696.94
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Cenicriviroc
8-[4-(2-Butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1-benzazocine-5-carboxamide;|(-)-8-[4-(2-Butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide; TB-652; Tobira

Cenicriviroc is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell.

Synonyms
8-[4-(2-Butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1-benzazocine-5-carboxamide; (-)-8-[4-(2-Butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide; TB-652; Tobira
CAS No
497223-25-3 Mesylate Salt: 497223-28-6
Molecular Formula
C41H52N4O4S
Molecular Weight
696.94
Appearance
White to off-white solid
Purity
≥95%
Solubility
DMF: 20mg/ml DMSO: 20mg/ml DMSO:PBS (pH 7.2) (1:1): 0.5mg/ml Ethanol: 5mg/ml
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010); Baba, M., et al.: Antimicrob. Agents Chemother., 49, 4584 (2005)
USBio References
No references available
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