Technical Data

447712
CAS Number
204398-90-3
Grade
Highly Purified
Molecular Formula
C₃₂H₄₅N₃O₂
Molecular Weight
503.72
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Drimentine A
(3S,5aS,10bS,11aS)-10b-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; [3S-[3α,5aα,10bα(1R*,4aR*,8aR*),11aβ]]-10b-[(Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione

Drimentine A is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.1 It is active against Gram-positive and Gram-negative bacteria, fungi, and yeast and has anthelmintic properties.

Synonyms
(3S,5aS,10bS,11aS)-10b-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; [3S-[3α,5aα,10bα(1R*,4aR*,8aR*),11aβ]]-10b-[(Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione
CAS No
204398-90-3
Molecular Formula
C₃₂H₄₅N₃O₂
Molecular Weight
503.72
Appearance
White to off-white powder
Purity
≥98%
Solubility
DMF, DMSO, Ethanol, Methanol
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Lacey, E., Power, M., Wu, Z., et al. Terpenylated diketopiperazines, (drimentines). WO1998009968A1, (1998).
USBio References
No references available
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