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448515 Etanidazole CAS: 22668-01-5

Specifications
References
CAS Number
22668-01-5
Grade
Highly Purified
Molecular Formula
C₇H₁₀N₄O₄
Molecular Weight
214.18
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide

Etanidazole is a kind of hypoxic radiosensitizer (a drug that sensitizes tumor cells to radiation therapy). Etanidazole is used in conjunction with Paclitaxel to treat glioma, and is also used with Carboplatin to treat advanced ovarian cancer.

Synonyms
N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide
CAS No
22668-01-5
Molecular Formula
C₇H₁₀N₄O₄
Molecular Weight
214.18
Appearance
White to off-white solid
Purity
≥97%
Melting Point
161-163°C
Solubility
DMSO (Slightly), Acetone (Slightly), Methanol (Slightly)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Brown, M.: Cancer Res., 59, 5863 (1999); Kumar, N., et al.: Biomaterials, 28, 886 (2007); Shulman, L., et al.: Int. J. Radiat. Oncol., 29, 545 (1994); Wang, F. & Wang, C.: J. Control. Release, 81, 263 (2002)
USBio References
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