Hydroxymethoxy-N-desmethyl Toremifene CAS NA

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452093 Hydroxymethoxy-N-desmethyl Toremifene CAS: NA

Specifications

References

CAS Number

Grade

Purified

Molecular Formula

C₂₆H₂₈ClNO₃

Molecular Weight

437.96

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

Hydroxymethoxy-N-desmethyl Toremifene is a derivative of Toremifene, an antiestrogen and antineoplastic. Toremifene is a nonsteroidal antiestrogen structurally similar to Tamoxifen. Toremifine has has been shown to reduce Ebola infection in rodents.

CAS No

N/A

Molecular Formula

C₂₆H₂₈ClNO₃

Molecular Weight

437.96

Purity

≥80%

Appearance

Pale brown to light brown solid

Melting Point

>133°C (dec.) (lit)

Solubility

DMSO (Slightly), Methanol (Slightly, Heated)

Method for Determining Identity

Proton NMR Spectroscopic and Mass Spectrometric Analysis

Elemental Analysis

Calculated: %C: 71.30, %H: 6.44, %N: 3.20

Atmosphere

Inert

Storage and Stability

Powder is stable for 6 months after receipt at -20°C. Hygroscopic. Under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Kallio, S., et al.: Cancer Chemother. Pharmacol., 17, 103 (1986), 2. Valavaara, R., et al.: Eur. J. Cancer Clin. Oncol., 24, 785 (1988); (3) 3. Chem. and Eng. News p9, July 4 (2016)