452093
CAS Number
NAGrade
PurifiedMolecular Formula
C₂₆H₂₈ClNO₃Molecular Weight
437.96EU Commodity Code
38220090Shipping Temp
RTStorage Temp
-20°CHydroxymethoxy-N-desmethyl Toremifene
Hydroxymethoxy-N-desmethyl Toremifene is a derivative of Toremifene, an antiestrogen and antineoplastic. Toremifene is a nonsteroidal antiestrogen structurally similar to Tamoxifen. Toremifine has has been shown to reduce Ebola infection in rodents.
Molecular Formula
C₂₆H₂₈ClNO₃
Appearance
Pale brown to light brown solid
Melting Point
>133°C (dec.) (lit)
Solubility
DMSO (Slightly), Methanol (Slightly, Heated)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
Elemental Analysis
Calculated: %C: 71.30, %H: 6.44, %N: 3.20
Storage and Stability
Powder is stable for 6 months after receipt at -20°C. Hygroscopic. Under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Kallio, S., et al.: Cancer Chemother. Pharmacol., 17, 103 (1986), 2. Valavaara, R., et al.: Eur. J. Cancer Clin. Oncol., 24, 785 (1988); (3) 3. Chem. and Eng. News p9, July 4 (2016)USBio References
No references available