A2296-74A
CAS Number
82189-04-6Grade
Highly PurifiedMolecular Formula
C36H50N2O8Molecular Weight
638.8EU Commodity Code
38220090Shipping Temp
Blue IceStorage Temp
-20°CAnsatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II)
Antibiotic T 23II, Mycotrienin II, T 23II
Also know as Mycotrienin II and Antibiotic T 23II, Ansatrienin B isolated from a Streptomyces sp. is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.
Solubility: Soluble in ethanol, methanol, DMF or DMSO
Related to: Ansatrienin A
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. |J. Biol. Chem. 1995, 270, 25949. 2. Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. Gann. 1983, 74, 759. 3. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. J. Antibiot. 1982, 35, 1467.USBio References
No references available