Ansatrienin B CAS 82189-04-6

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A2296-74A Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II) CAS: 82189-04-6

Specifications

References

CAS Number

82189-04-6

Grade

Highly Purified

Molecular Formula

C36H50N2O8

Molecular Weight

638.8

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

Antibiotic T 23II, Mycotrienin II, T 23II

Also know as Mycotrienin II and Antibiotic T 23II, Ansatrienin B isolated from a Streptomyces sp. is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.

Purity: >95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO

Related to: Ansatrienin A

Source

Streptomyces sp

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. |J. Biol. Chem. 1995, 270, 25949. 2. Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. Gann. 1983, 74, 759. 3. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. J. Antibiot. 1982, 35, 1467.