A3884
CAS Number
577-64-0Grade
Highly PurifiedMolecular Formula
C17H16O8Molecular Weight
348.3EU Commodity Code
38220090Shipping Temp
Blue IceStorage Temp
+4°CAsterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A
A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells.
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Source
Aspergillus terreus
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced |tube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552. |2. Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al. J. Antibiot. 1992, 45, 1684. |3. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: |isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, |questin and questinol. Mahmoodian A. et al. Biochem. J. 1964, 92, 369.USBio References
No references available