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B1078-01J S-(+)-N-3-Benzylnirvanol CAS: 790676-40-3

Specifications
References
CAS Number
790676-40-3
Grade
Highly Purified
MDL Number
MFCD09840024
Molecular Formula
C₁₈H₁₈N₂O₂
Molecular Weight
294.35
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
(5S)-5-Ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione, 5-Ethyl-5-phenyl-3-(phenylmethyl)hydantoin

Potent and selective human CYP2C19 inhibitor. (+)-N-3-Benzylnirvanol may be used as a cytochrome P450 2C19 (CYP2C19) inhibitor in a comparison study to treat cocktail and individual substrates for the screening for potent cytochrome P450 (CYP) inhibition. It may also be used in comparative studies to investigate its potential as CYP and non-CYP selective inhibitors of CYP2C19 in suspended human hepatocytes.

Synonyms
(5S)-5-Ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione, 5-Ethyl-5-phenyl-3-(phenylmethyl)hydantoin
CAS No
790676-40-3
Molecular Formula
C₁₈H₁₈N₂O₂
Molecular Weight
294.35
Appearance
White to off-white solid
Purity
≥97%
Melting Point
147-150°C
Solubility
DMSO (Slightly), Methanol (Slightly, Sonicated)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Suzuki, H., et al.: Drug Metab. Dispos., 30, 235 (2002), Robert, L., et al.: Drug Metab. Dispos., 31, 343 (2003)
USBio References
No references available
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