Technical Data

C2447-35-APC
Grade
Affinity Purified
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
BSA Free
CD112 (Poliovirus Receptor Related 2, PRR2) (APC)

CD112 Poliovirus Receptor Related 2 (PRR2), is a new surface molecule, which has been reported to be homologous to the poliovirus receptor (CD155). Studies demonstrate that PRR2 expression is restrictred to the myelomonocytic and megakaryocytic lineages. PRR2 expresion has also been detected on haematopoeitic progenitors expressing CD34.

Applications
Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Not recommended for use in Western Blot. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry: Frozen sections Optimal working dilutions to be determined by researcher.
Recommended Secondary Antibody
I1904-14C: IgG, Fc (HRP) Pab Gt xMo I1904-23: IgG, X-Adsorbed (FITC) Pab Gt xMo
Recommended Negative Control
I1904-78R: IgG1 Murine Negative Control
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Lopez, M. et al. (1998). The Human Poliovirus Receptor Related 2 protein is a new Hematopoietic/Endothelial Homophilic Adhesion Molecule. Blood 92: 4602-4611. 2. Goyert, S.M. (1998) White cell differentiation antigens, Myeloid Antigens: section report. Leucocyte typing VI. Kishimoto, T. et al. eds (Garland Publishing Inc, New York) p. 956-957.
USBio References
No references available
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