Technical Data

D3727-25
CAS Number
4673-26-1
Grade
Highly Purified
Molecular Formula
C12H8ClI
Molecular Weight
314.55
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Diphenyleneiodonium Chloride (DPI Chloride)
DPI Chloride; Dibenz[b,d]iodolium Chloride

Binds strongly to flavoproteins and thus inhibits NO synthase, NADG reductase and NADPH oxidase.

Synonyms
DPI Chloride; Dibenz[b,d]iodolium Chloride
CAS No
4673-26-1
Molecular Formula
C12H8ClI
Molecular Weight
314.55
Appearance
White to Off-White Solid
Purity ~90%
Melting Point
>300°C (dec.)
Solubility
DMSO-Water 5mg in 1.7ml of H2O:DMSO 40:60; 10mg in 1.1ml H2O:DMSO 10:90
Method for Determining Identity
Proton NMR (DMSO-d6) Spectroscopic analysis and Mass Spectrometric analysis
TLC Conditions
As Reported
Chloride Content
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Jones, et al.: Biochem J., 265, 95 (1990), 2. Stuehr, et al.: FASEB J., 5, 98 (1991), 3. Wang, Y-X, et al.: J. of Pharmacology & Exp. Therap., 265, 1 , 263 (1993) 4. Circulation Research, 74 (6), 1142 (1994), 5. Cruz, T.F., et al.: J.B.C., 271, 26, 15703(1996)
USBio References
No references available
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