Diphenyleneiodonium Chloride CAS 4673-26-1

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D3727-25 Diphenyleneiodonium Chloride (DPI Chloride) CAS: 4673-26-1

Specifications

References

CAS Number

4673-26-1

Grade

Highly Purified

Molecular Formula

C12H8ClI

Molecular Weight

314.55

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

DPI Chloride; Dibenz[b,d]iodolium Chloride

Binds strongly to flavoproteins and thus inhibits NO synthase, NADG reductase and NADPH oxidase.

Synonyms

DPI Chloride; Dibenz[b,d]iodolium Chloride

CAS No

4673-26-1

Molecular Formula

C12H8ClI

Molecular Weight

314.55

Appearance

White to Off-White Solid

Purity ~90%

Melting Point

>300°C (dec.)

Solubility

DMSO-Water 5mg in 1.7ml of H2O:DMSO 40:60; 10mg in 1.1ml H2O:DMSO 10:90

Method for Determining Identity

Proton NMR (DMSO-d6) Spectroscopic analysis and Mass Spectrometric analysis

TLC Conditions

As Reported

Chloride Content

As Reported

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Jones, et al.: Biochem J., 265, 95 (1990), 2. Stuehr, et al.: FASEB J., 5, 98 (1991), 3. Wang, Y-X, et al.: J. of Pharmacology & Exp. Therap., 265, 1 , 263 (1993) 4. Circulation Research, 74 (6), 1142 (1994), 5. Cruz, T.F., et al.: J.B.C., 271, 26, 15703(1996)