Entecavir CAS 142217-69-4

CAS Number

142217-69-4

Grade

Highly Purified

Molecular Formula

C12H15N5O3

Molecular Weight

277.28

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-Purin-6-one; Baraclude; BMS 200475; SQ 34676

An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.

Melting Point

As Reported

Method for Determining Identity

Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis

Solubility

As Reported

TLC Conditions

As Reported

Specific Rotation

As Reported

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Temperature, Light and Moisture Sensitive.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

References

Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006)