N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide;|A 4942; Asta Z 4942; Cyfos; Holoxan; Ifex; Ifomide; Iphosphamide; MJF 9325; Mitoxana; NSC 109724; Naxamide
A cytostatic agent, related structurally to cyclophosphamide.
Synonyms
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Ifex; Ifomide; Iphosphamide; MJF 9325; Mitoxana; NSC 109724; Naxamide
Molecular Formula
C7H15Cl2N2O2P
Solubility
Water, Methanol
Method for Determining Identity
Proton NMR (D2O), 31P NMR (D2O) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2: Dichloromethane: Methanol= 9-1; Visualized with UV and KMnO4; Single spot, Rf=0.4.
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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