M4000
CAS Number
50-07-7Grade
Molecular Biology GradeMolecular Formula
C15H18N4O5Molecular Weight
334.3EU Commodity Code
38220090UN DOT Shipping
UN2811 PGIIShipping Temp
Blue IceStorage Temp
4°CMitomycin C Pure (NaCl-Free)
Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,’3’:3,4]pyrrolo[1,2-a]indole-4,7-dione
Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Mitomycin C is an anti-tumor antibiotic that causes base pair disruption in the cellular nucleic acid by combining with resident guanine residues. Used as a therapeutic antineoplastic agent.
Synonyms
Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,’3’:3,4]pyrrolo[1,2-a]indole-4,7-dione
Molecular Formula
C15H18N4O5
Appearance
Purple-grey to deep blue powder
Identification (IR)
Conforms to Reference
Identification (UV/357nm)
95–105% of Reference Standard
Solubility (0.5mg/ml dH2O)
Purple-blue, clear solution
Storage and Stability
May be stored at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
US Biological application reference: Chaw, K.C. et al.,(2007) Lab Chip 7:1041–1047. 1. Stevens, et al., J. Med Chem., 8: 1 (1965). 2. Tomasz, M., et al., Science, 235: 1204 (1987). 3. Schwartz, G.K., et al., J. Nat’l Cancer Inst., 87: 1394 (1995).USBio References
US Biological application reference: Chaw, K.C. et al.,(2007) Lab Chip 7:1041–1047.