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M4000 Mitomycin C Pure (NaCl-Free) CAS: 50-07-7

Specifications
References
CAS Number
50-07-7
Grade
Molecular Biology Grade
Molecular Formula
C15H18N4O5
Molecular Weight
334.3
EU Commodity Code
38220090
UN DOT Shipping
UN2811 PGII
Shipping Temp
Blue Ice
Storage Temp
4°C
Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,’3’:3,4]pyrrolo[1,2-a]indole-4,7-dione

Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Mitomycin C is an anti-tumor antibiotic that causes base pair disruption in the cellular nucleic acid by combining with resident guanine residues. Used as a therapeutic antineoplastic agent.

Synonyms
Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,’3’:3,4]pyrrolo[1,2-a]indole-4,7-dione
CAS No
50-07-7
Molecular Formula
C15H18N4O5
Molecular Weight
334.3
Appearance
Purple-grey to deep blue powder
Assay
≥ 970ug/mg
Identification (IR)
Conforms to Reference
Identification (UV/357nm)
95–105% of Reference Standard
pH (5mg/ml)
5.0-7.5
Water
≤ 2%
Solubility (0.5mg/ml dH2O)
Purple-blue, clear solution
Storage and Stability
May be stored at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
US Biological application reference: Chaw, K.C. et al.,(2007) Lab Chip 7:1041–1047. 1. Stevens, et al., J. Med Chem., 8: 1 (1965). 2. Tomasz, M., et al., Science, 235: 1204 (1987). 3. Schwartz, G.K., et al., J. Nat’l Cancer Inst., 87: 1394 (1995).
USBio References
US Biological application reference: Chaw, K.C. et al.,(2007) Lab Chip 7:1041–1047.
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