N2561-90X
CAS Number
51095-86-4Grade
Highly PurifiedMolecular Formula
C₁₀H₁₄N₂OMolecular Weight
178.19EU Commodity Code
38220090Shipping Temp
RTStorage Temp
-20°C(1’S,2'S)-Nicotine 1'-Oxide ((1’S,2'S)-trans-Nicotine 1'-Oxide)
(1’S,2’S)-trans-Nicotine 1’-Oxide; 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]pyridine; (1S-cis)-3-(1-Methyl-2-pyrrolidinyl)pyridine N-Oxide; (1S,2S)-syn-Nicotine N'-oxide; (1'S,2'S)-trans-Nicotine-1'-N-oxide; 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]|pyridine; Nicotine-cis-N-oxide; (1S-cis)-3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine
Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Solubility
Chloroform, Ethanol, Methanol, Water
Form
White to Pale Orange Solid
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Phillipson, J.D., and Handa, S.S.: Phytochemistry, 14, 2683 (1975)USBio References
No references available