(αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile Hydrochloride; (R)-Norverapamil Hydrochloride
The chiral metabolite of Verapamil.
Synonyms
(αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile Hydrochloride; (R)-Norverapamil Hydrochloride
Molecular Formula
C26H36N2O4 HCl
Form
Supplied as a white to offf-white solid
Melting Point
>165ºC (dec)
Solubility
Chloroform (Slightly) Methanol (Slightly)
Method for Determining Identity
Proton NMR and MS
TLC Conditions
SiO2; Dichloromethane: Methanol (9:1). Visualized with UV and KMnO4 (single spot; Rf=0.40)
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
TDS
NCBI
UniProt
Tech Support
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