Pneumocandin B0
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of b-(1,3)- D-glucan, an essential component of the cell wall of susceptible fungi.
Source
Pneumocandin B0 from unidentified fungus.
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Concentration
Not determined
Form
Supplied as a white to off-white solid.
