Technical Data

S0058-50
CAS Number
53003-10-4
Grade
Highly Purified
Molecular Formula
C42H70O11
Molecular Weight
751
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Salinomycin

Salinomycin is a polyether ionophore with broad spectrum Gram +ve and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used in animal health for control of coccidia and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is > 100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active.

Source
Salinomycin from Streptomyces sp.
Molecular Weight
751D
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity
≥95% (HPLC)
Form
Supplied as a white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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