S6607
CAS Number
163391-76-2Grade
Highly PurifiedMolecular Formula
C23H31NO4Molecular Weight
385.5EU Commodity Code
38220090Shipping Temp
Blue IceStorage Temp
+4°CStachybotrylactam (2-deoxy Antibiotic F1839A)
2-deoxy Antibiotic F1839A
Isolated from a Stachybotrys sp., this unusual spirodihydrobenzofuranlactam mycotoxin shows immuno-suppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition.
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Total synthesis and structure revision of Stachybotrys spirolactams. Deng W.P. et al. J. Org. Chem. |2003, 68, 7422. |2. Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease |produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. Roggo B.E. et al. J. |Antibiot. 1996, 49, 13. |3. Stachybotrys toxins I. Jarvis B.B. et al. Nat. Toxins 1995, 3, 10.USBio References
No references available