S7990
CAS Number
149647-78-9Grade
Highly PurifiedMolecular Formula
C14H20N2O3Molecular Weight
264.32EU Commodity Code
38220090UN DOT Shipping
UN3077 PGIIIShipping Temp
RTStorage Temp
-20°CSuberoylanilide Hydroxamic Acid (SAHA, Zolinza, Vorinostat)
SAHA; N-Hydroxy-N’-phenyloctanediamide; N-Hydroxy-N’-phenyloctanediamide; Zolinza; Suberoylanilide-hydroxamic acid, Vorinostat
A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
Appearance
Supplied as a white to off-white solid
TLC Conditions
SiO2; Chloroform: Methanol: Water: Acetic Acid; 75: 25: 2: 2; Visualized with UV and by exposure to iodine vapor.
Calculated
C: 63.62%, H: 7.63%, N: 10.60%
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Form
Supplied as a white to off-white solid
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
