Tenofovir
[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid;|(R)-9-(2-Phosphonomethoxypropyl)adenine
Acyclic phosphonate nucleotide analogue. Used as an anti-HIV agent.
Solubility: Warm DMSO, Warm Water
Method for Determining Identity: Proton NMR spectroscopic and mass spectrometric analyses
TLC Conditions: SiO2; Dichloromethane: Methanol: Acetonitrile: 1M HCl (1:2:6:1); Visualized with UV; Single spot (Rf=0.45)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
