Technical Data

T2900
CAS Number
7365-44-8
Grade
Molecular Biology Grade
MDL Number
MFCD00007532
Molecular Formula
C₆H₁₅NO₆S
Molecular Weight
229.25
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
TES Free Acid
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid; N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]taurine (7CI,8CI); 2-[[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]ethanesulfonic Acid;|2-[[Tris(hydroxymethyl)methyl]amino]ethanesulfonic Acid; N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid; N-|[Tris(hydroxymethyl)methyl]aminoethanesulfonic Acid; TES (Buffering Agent)

TES is a biological buffer (zwitterionic) designed by Good, et al. Typically referred to as Good’s Buffer useful in cell culture media formulations. Selection of biological buffer systems should include the following criteria: exclusion by biological membranes, low absorption between 240-700nm, chemically stable, and stable to temperature and concentration changes.

TES is a structural analog to the ethanesulfonic acid series of biological buffers to meet these criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pKa with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range,an deasily synthesized.
Synonyms
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid; N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]taurine (7CI,8CI); 2-[[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]ethanesulfonic Acid; 2-[[Tris(hydroxymethyl)methyl]amino]ethanesulfonic Acid; N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid; N- [Tris(hydroxymethyl)methyl]aminoethanesulfonic Acid
CAS No
7365-44-8
Molecular Formula
C₆H₁₅NO₆S
Appearance
White crystalline powder
Purity
≥98%
Solubility (10%, H2O)
Colorless, clear, complete
pKa (20°C)
7.4
pH Buffering Capacity
6.8-8.2
Water (Karl Fisher)
≤0.1%
Absorbance (A280, 0.1M, dH2O)
≤0.05
Absorbance (A260, 0.1M, dH2O)
≤0.05
Storage
RT

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Good, N. E., et al., Biochemistry 5:467 (1966)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net