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V2121-49L1 Verapamil-d6 Hydrochloride CAS: 1185032-80-7

Specifications
References
CAS Number
1185032-80-7
Grade
Highly Purified
Molecular Formula
C₂₇H₃₃D₆ClN₂O₄
Molecular Weight
497.1
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile-d6 Hydrochloride; Berkatens-d6; Calan-d6; Cardibeltin-d6; Dignover-d6; Isoptin-d6; Veracim-d6; Veramex-d6; Zolvera-d6;

A deuterated calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV).

Synonyms
a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile-d6 Hydrochloride; Berkatens-d6; Calan-d6; Cardibeltin-d6; Dignover-d6; Isoptin-d6; Veracim-d6; Veramex-d6; Zolvera-d6;
CAS No
1185032-80-7 Free Base: 23313-68-0; Unlabeled: 152-11-4
Molecular Formula
C₂₇H₃₃D₆ClN₂O₄
Molecular Weight
497.1
Appearance
White solid
Purity
≥98%
NMR
Conforms to structure
FT-IR
Conforms to structure
MS
Conforms to structure
TLC Conditions
SiO2; Dichloromethane : Methanol = 9 : 1; Visualized with UV and KMnO4; Single Spot, Rf = 0.40.
Melting Point
139-141°C
Chloride
~7%
Solubility
Chloroform (Slightly), Methanol (Slightly)
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)
USBio References
No references available
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