036243
Grade
Affinity PurifiedSpecificity
HumanGene ID
2863Gene #
GPR39Applications
E WBAccession Number
O43194; NP_001499.1EU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CGPR39, CT (GPR39, G-protein coupled receptor 39)
GPR39, G-protein coupled receptor 39
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Sharir, H., et al. J. Biol. Chem. 285(34):26097-26106(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Holst, B., et al. J. Biol. Chem. 285(6):3973-3985(2010)|Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :|Zhang, Y., et al. J. Endocrinol. 199(3):457-470(2008)USBio References
No references available