Rheumatoid Factor (RF) Concentrate, Human
Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. Rheumatoid arthritis is a systemic disease characterized by chronic proliferation and inflammation of joint cartilage and supporting structures. RA is mainly defined by clinical criteria, in which systematic pathogenetic studies have been hampered by doubts about the presence of common pathogenetic mechanisms and the relative lack of unique laboratory findings. IgG rheumatoid factor has been reported to be present in sera of patients with rheumatoid arthritis both with and without IgM rheumatoid factor activity.
This product is highly concentrated for minimum volume additions for control/calibrator manufacturing versus plasma or serum, saving money on other material components. Native-sourced, mimicking elevated RF human donor samples during assay interference studies. Ideal for spike-interference studies in assay development and validation.
Appearance
Supplied as a gray to brown, hazy liquid in PBS, pH 7.2, 0.02% ProClin-300.
Specific Activity
As Reported
Total Protein
As Reported
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
