475753
Grade
Affinity PurifiedSpecificity
Recognizes human ASIC4.Gene ID
55515Gene #
ASIC4Applications
WBAccession Number
NP_061144EU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CASIC4 (Acid Sensing Ion Channels 4, Acid-sensing (Proton-gated) Ion Channel Family Member 4)
ASIC4, BNAC4, MGC17248, MGC24860, ACCN4
ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ACCN4 is predominantly expressed in the pituitary gland, and might be a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.