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349889 EMCN, Recombinant, Human, aa19-190, His-Tag (Endomucin)

Specifications
References
Purity
~90% (SDS-PAGE)
Accession Number
NP_057326
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

Endomucin, also called endothelial sialomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. This protein expressed in heart, kidney and lung.

Source
Recombinant protein corresponding to aa19-190 of human EMCN, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~20.5kD
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMNSTGV LEAANNSLVV TTTKPSITTP NTESLQKNVV TPTTGTTPKG TITNELLKMS LMSTATFLTS KDEGLKATTT DVRKNDSIIS NVTVTSVTLP NAVSTLQSSK PKTETQSSIK TTEIPGSVLQ PDASPSKTGT LTSIPVTIPE NTSQSQVIGT EGGKNASTSA TSRSYSS
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
~90% (SDS-PAGE)
Concentration
~0.1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 100mM sodium chloride, 1mM DTT, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Kinoshita M, et al. (2001) FEBS Lett 499 (1-2): 121-6., 2. Kuhn A., et al. (2002) J. Invest. Dermatol. 119:1388-139.
USBio References
No references available
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