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350163 PDPN, Recombinant, Human, aa99-207, His-Tag (Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 Antigen, T1-alpha, T1A, GP36, PSEC0003, PSEC0025)

Specifications
References
Purity
≥95% (SDS-PAGE)
Accession Number
NP_006465
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

Podoplanin(PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor.

Source
Recombinant protein corresponding to aa99-207 of human PDPN, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~13.4kD
Applications
Suitable for use in SDS-PAGE. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MASTGQPEDD TETTGLEGGV AMPGAEDDVV TPGTSEDRYK SGLTTLVATS VNSVTGIRIE DLPTSESTVH AQEQSPSATA SNVATSHSTE KVDGDTQTTV EKDGLSTVTL
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥95% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in 20mM Tris, pH 7.5, 0.1M sodium chloride.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Wicki A., et al. (2006) Br J Cancer. 96(1):1-5. 2. Zimmer G., et al. (1999) Biochem J. 341, 277-84.
USBio References
No references available
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