033932
Grade
Affinity PurifiedPurity
Purified by Protein A affinity chromatography.Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.Specificity
HumanEU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CCLC, CT (CLC, Eosinophil lysophospholipase, Charcot-Leyden crystal protein, Galectin-10, Lysolecithin acylhydrolase)
CLC, Eosinophil lysophospholipase, Charcot-Leyden crystal protein, Galectin-10, Lysolecithin acylhydrolase
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)|Bryborn, M., et al. Allergy 65(2):220-228(2010)|De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :|Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106(24):9731-9736(2009)|Kubach, J., et al. Blood 110(5):1550-1558(2007)USBio References
No references available