037172
Grade
Affinity PurifiedPurity
Purified by Protein A and peptide affinity chromatographyForm
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azideSpecificity
Recognizes human JAG1EU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CJAG1, CT (JAG1, JAGL1, Protein jagged-1, CD339)
JAG1, JAGL1, Protein jagged-1, CD339
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Applications
Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Flow Cytometry (Indirect): 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Foldi, J., et al. J. Immunol. 185(9):5023-5031 (2010). 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253 (2010). 3. Kerns, D., et al. Schizophr. Res. 120 (1-3), 150-158 (2010). 4. Siar, C.H., et al. Eur. J. Med. Res. 15(4):180-184 (2010). 5. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)USBio References
No references available