TUDCA dihydrate; UR 906 dihydrate; Taurolite dihydrate; 3α,7β-Dihydroxy-5β-cholan-24-oic acid n-(2-sulfoethyl)amide dihydrate
Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
Synonyms
TUDCA dihydrate; UR 906 dihydrate; Taurolite dihydrate; 3α,7β-Dihydroxy-5β-cholan-24-oic acid n-(2-sulfoethyl)amide dihydrate
CAS No
117609-50-4,14605-22-2
Molecular Formula
C26H45NO6S·2H2O
Appearance
White to off-white powder
Infrared Spectrum
Conforms to reference
Related Substances
Ursodeoxycholic acid: ≤1.5% Taurine: ≤1%
Solubility
DMSO: 83.33mg/ml (155.54mM); Water:12.5mg/ml (25.02mM)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C.