Technical Data

007449
CAS Number
84-52-6
Grade
Highly Purified
Molecular Formula
C₉H₁₄N₃O₈P
Molecular Weight
323.2
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Cytidine 3'-Monophosphate
3'--Cytidylic Acid; 3'-CMP; Cytidine 3'-phosphate

A metabolite of Cytidine. A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.

Synonyms
3'--Cytidylic Acid; 3'-CMP; Cytidine 3'-phosphate
CAS No
84-52-6
Molecular Formula
C₉H₁₄N₃O₈P
Molecular Weight
323.2
Appearance
White to off-white solid
Purity
≥95%
Melting Point
>142°C (dec.)
Solubility
Water (Slightly); PBS (pH 7.2): slightly soluble
Storage and Stability
Store at -20°C. Hygroscopic, Under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Unemoto, T., Takahashi, F., and Hayashi, M. Relationship between the active sites of 2',3'-cyclic phosphodiesterase with 3'-nucleotidase activity purified from Vibrio alginolyticus. Biochim. Biophys. Acta 185(1), 134-142 (1969).|2. Moussaoui, M., Nogués, M.V., Guasch, A., et al. The subsites structure of bovine pancreatic ribonuclease A accounts for the abnormal kinetic behavior with cytidine 2',3'-cyclic phosphate. The Journal of Biological Chemisty 273(40), 25565-25572 (1998).|3. Kandeel, M., and Al-Taher, A. Metabolic drug targets of the cytosine metabolism pathways in the dromedary camel (Camelus dromedarius) and blood parasite Trypanosoma evansi. Trop. Anim. Health Prod. 52(6), 3337-3358 (2020).|4. Doucet, N., Jayasundera, T.B., Simonović, M., et al. The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding. Proteins 78(11), 2459-2468 (2010).|5. Phizicky, E., et al.: J. Biol. Chem., 267, 4577 (1992)|6. Murguia, J., et al.: Science, 267, 232 (1995)|7. Lei, M., et al.: Biochemistry, 41, 14560 (2002)
USBio References
No references available
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