2-Deoxy-2-fluoro-D-galactose
3-Fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol
2-Deoxy-2-fluoro-D-galactose, also called 3-fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol, can be added to the medium of primary cultured rat hepatocytes to inhibit N-glycosylation of proteins. Immunoglobulin G (IgG) is the most common antibody found in blood and 2-deoxy-2-fluoro-D-galactose modifies the galactosylation of the N-linked glycan in the IgG-Fc receptor.
Synonyms
3-Fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol
Molecular Formula
C6H11FO5
Appearance
White to off-white powder
Specific Optical Rotation [alpha]D c=0.5, water, 24hrs)
89 to 95º
1H-NMR Spectrum
Conforms to reference
Storage and Stability
Store at -20ºC. Stable for 12 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.