Technical Data

351220
Grade
Highly Purified
Accession Number
NP_004456
Molecular Weight
22
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
FGF10, Recombinant, Human, aa38-208, His-Tag|(Fibroblast growth factor 10, Keratinocyte growth factor 2)

FGF10, also known as fibroblast growth factor 10, exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. FGF10 is also implicated to be a primary factor in the process of wound healing.

Recombinant protein corresponding to aa38-208 from human FGF10, fused to His-tag at N-terminal expressed in E. coli.
Molecular Weight
~22.0kD(196aa)
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQALGQ DMVSPEATNS SSSSFSSPSS AGRHVRSYNH LQGDVRWRKL FSFTKYFLKI EKNGKVSGTK KENCPYSILE ITSVEIGVVA VKAINSNYYL AMNKKGKLYG SKEFNNDCKL KERIEENGYN TYASFNWQHN GRQMYVALNG KGAPRRGQKT RRKNTSAHFL PMVVHS
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥95%(SDS-PAGE)
Concentration
~0.1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl pH8.0, 0.2M sodium chloride, 2mM DTT, 2mM EDTA, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Entesarian M., et al. (2005) Nat. Genet. 37:125-127 2. Milunsky J.M., et al. (2006) Clin. Genet. 69:349-354
USBio References
No references available
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