A0910
CAS Number
30827-99-7Grade
Molecular Biology GradeMDL Number
MFCD00132962Molecular Formula
C8H10FNO2S•HClMolecular Weight
239.69EU Commodity Code
38220090UN DOT Shipping
UN3261 PGIIShipping Temp
RTStorage Temp
4°CAEBSF Hydrochloride
4-(2-Aminoethyl)-bezenesulfonylfluoride•HCl
Specific irreversible inhibitor of serine proteases such as thrombin, plasmin, kallikrein, chymotrypsin and trypsin. It is a non-toxic alternative to PMSF or DFP. AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25mM.
Synonyms
4-(2-Aminoethyl)-bezenesulfonylfluoride•HCl
Molecular Formula
C8H10FNO2S•HCl
Appearance
White to off-white powder.
Solubility
Colorless, clear, complete in water. H2O: soluble, 50mg/ml (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)
Storage and Stability
May be stored at 4°C Stable for 12 months after receipt. Hygroscopic. Keep tightly closed and desiccated. Light sensitive.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Sastalla, I. et al., (2013) PLoS One 8(10): e76955. doi:10.1371/journal.pone.0076955. 1. Walsmann, P., et al., Acta biol. med. germ. 28: 577-585 (1972). 2. Marwardt, F., et al., Thrombosis Res. 2: 343-348 (1973). 3. Taylor, J.A., et al., Immunology 86: 629-635 (1995). 3. Pomerantsev AP, et al. Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases. PLoS One. 2017 Aug 22;12(8):e0183346. doi: 10.1371/journal.pone.0183346. eCollection 2017.USBio References
1. Sastalla, I. et al., (2013) PLoS One 8(10): e76955. doi:10.1371/journal.pone.0076955. 2. Pomerantsev AP, et al. Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases. PLoS One. 2017 Aug 22;12(8):e0183346. doi: 10.1371/journal.pone.0183346. eCollection 2017.