DYNLRB1, Recombinant, Human (Dynein Light Chain Roadblock-type1, Bithoraxoid-like Protein, LP, Dynein Light Chain 2A, Cytoplasmic, Dynein-Associated Protein Km23, Roadblock Domain-containing Protein 1, BITH, DNCL2A, DNLC2A, ROBLD1, HSPC162)
Dynein light chain roadblock-type, also known as DYNLRB1 is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.
Source
Recombinant corresponding to aa1-96 of human DYNLRB1 human, fused to His-tag at C-terminus, expressed in E.coli.
AA Sequence
MAEVEETLKR LQSQKGVQGI IVVNTEGIPI KSTMDNPTTT QYASLMHSFI LKARSTVRDI DPQNDLTFLR IRSKKNEIMV APDKDYFLIV IQNPTELEHH HHHH
Molecular Weight: 11.9kD (104aa) confirmed by MALDI-TOF
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Form
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
