Technical Data

G2006-10
CAS Number
37758-47-7
Grade
Molecular Biology Grade
Molecular Formula
C73H131N3O31•Na
Molecular Weight
1568.8
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Ganglioside GM1, Bovine, Sodium Salt (Monosialoganglioside GM1)
Monosialoanglioside GM1, sodium salt (Bovine brain)

A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera toxin. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system. It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorylation and synaptic function.

Synonyms
Monosialoanglioside GM1, sodium salt (Bovine brain)
Nomenclature
[II3Neu5AcGgOse4Cer][b-Gal-(1-3)-b-GalNAc-(1-4)-[a-Neu5Ac-(2-3)]-b-Gal(1-4)-b-Glc-(1-1')-Cer]
CAS No
37758-47-7
Molecular Formula
C73H131N3O31
Molecular Weight
1546.82
Purity (HPLC)
≥95%
Appearance
White to off-white powder
FT-IR Spectrum
Conforms to reference spectrum
Storage and Stability
Store at -20ºC. Product is stable for 6 months from time of receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Svennerholm, L., et al.: Structure and Function of Gangliosides, New York, Plenum (1980). 2. Fishman, P.H., J. Membr. Biol. 69: 85 (1982).
USBio References
No references available
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