2-(N-Hexadecanoylamino)-4-nitrophenylphosphocholine, Hydroxide (HDA-PC)
Reported to be useful in detection and diagnosis of Niemann-Pick disease in humans.
Solubility
DMSO, Methanol, Water
Method for determining identity
1H NMR (CD3OD, D2O), 31P NMR (CD3OD, D2O), and MS. 1H NMR, 31P NMR, and MS conform to structure.
Elemental Analysis
%C:53.00, %H: 8.76, N%: 7.60
TLC conditions
SiO2; Dichloromethane : Methanol : Ammonium Hydroxide = 8 : 2 : 1; Visualized with UV and AMCS; Single Spot, Rf = 0.30.
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
