S6505-02E
Grade
PurifiedSpecificity
Recognizes human SRC1.Applications
E WBAccession Number
NP_003734Molecular Weight
156.757EU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CSRC1, NT (Nuclear Receptor Coactivator 1, NCoA-1, Steroid Receptor Coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal Carcinoma Antigen NY-REN-52, Class E Basic Helix-loop-helix Protein 74, bHLHe74, NCOA1)
SRC1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.
Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Lavery,D.N.,Biochemistry 47(11), 3352-3359 (2008). 2. Wang,S., J. Biol. Chem. 282(5), 2765-2775 (2007).USBio References
No references available