TARC, Recombinant, Human (Thymus and Activation Regulated Chemokine, CCL17, ABCD-2)
TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells.
Recombinant Human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Biological Activity
Determined by its ability to chemoattract human T cells using a concentration range of 1-10ng/ml.
Amino Acid Sequence
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Form
Supplied as a lyophilized powder. Reconstitute with sterile dH2O to 0.1-1mg/ml.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
