Human IgG based monoclonal antibodies (mAbs) are the fastest-growing category of therapeutics for cancer therapy. Several monoclonal antibodies have received FDA approval for the treatment of a variety of solid tumors and hematological malignancies. Several mechanisms of tumor cell killing by antibodies (mAbs) can be summarized as: direct action through receptor blockade or induction of apoptosis; immune-mediated cell killing by complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC) or regulation of T cell function. United States Biological is pleased to offer one of the largest selections of ELISA Kits for research-grade antibodies. These ELISA Kits can be used to study dose-pendent pharmacokinetics as well as to identify biomarkers for (non-)response and risk factors for adverse drug reactions.
Key Features
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Rituximab. This standard curve was generated with the supplied calibrator using the recommended conditions and diluted 1 in 50 to give a final concentration range of 100-5ng/ml. Each sample was run with 6 replicates. Intra-assay coefficient of variance is <10%.
Trastuzumab. This standard curve was generated with the supplied calibrator using the recommended conditions and diluted 1 in 50 to give a final concentration range of 40ng/ml to 1.25ng/ml. Each sample was run with 6 replicates. Intra-assay coefficient of variance is <10%.
Bevacizumab. The standard curve below was generated with the supplied calibrator using the recommended conditions and diluted 1 in 50 to give a final concentration range of 50-1.56ng/ml. Each sample was run with 6 replicates. Intra-assay coefficient of variance is <10%.
| Catalog # | Product |
|---|---|
| 384854 | Adalimumab (Humira®) BioAssay™ ELISA Kit |
| 384855 | Anti-PEG BioAssay™ ELISA Kit (Human IgG Specific) (Polyethylene Glycol) |
| 384856 | Anti-PEG BioAssay™ ELISA Kit (Human IgM Specific) (Polyethylene Glycol) |
| 384857 | Anti-PEG BioAssay™ ELISA Kit (Mouse IgG Specific) (Polyethylene Glycol) |
| 384858 | Anti-PEG BioAssay™ ELISA Kit (Mouse IgM Specific) (Polyethylene Glycol) |
| 384859 | Bevacizumab (Avastin®) BioAssay™ ELISA Kit |
| 384860 | Cetuximab (Erbitux®) BioAssay™ ELISA Kit |
| 384861 | Etanercept (Enbrel®) BioAssay™ ELISA Kit |
| 384862 | Infliximab (Remicade®) BioAssay™ ELISA Kit |
| 384863 | Natalizumab (Tysabri®) BioAssay™ ELISA Kit |
| 384864 | Omalizumab (Xolair®) BioAssay™ ELISA Kit |
| 384865 | Rituximab (Rituxan®) BioAssay™ ELISA Kit |
| 384866 | Rituximab (Rituxan®) Immunogenicity BioAssay™ ELISA Kit |
| 384867 | Tocilizumab (Actemra®) BioAssay™ ELISA Kit |
| 384868 | Trastuzumab (Herceptin®) BioAssay™ ELISA Kit |
| 384869 | Trastuzumab (Herceptin®) Immunogenicity BioAssay™ ELISA Kit |
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