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Anti -FLT4 (Fms-like tyrosine kinase 4, Vascular endothelial growth factor receptor 3, VEGFR3)
Anti -FLT4 (Fms-like tyrosine kinase 4, Vascular endothelial growth factor receptor 3,
VEGFR3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
|
E B |
|
| This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (EC’s) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV). | | | Catalog # | 030233 | | Applications | Western Bloting: 1:500-1:2000. | | ELISA: Suggested dilution 1:10000. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 13B311 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Ascites fluid, 0.03% sodium azide. | | Purity | Ascites | | Immunogen | Purified recombinant fragment of human FLT4 expressed in E. coli. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | PCL; FLT41; LMPH1A; VEGFR3; FLT4 |
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